Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022576 | 0.89 | KMT2A (0.60) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL9874630 | 0.88 | KMT2A (0.50) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL8322999 | 0.87 | KMT2A (0.58) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL23144946 | 0.86 | KMT2A (0.57) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL29843236 | 0.86 | KMT2A (0.57) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL8564446 | 0.84 | KMT2A (0.55) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL2280172 | 0.78 | KMT2A (0.54) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL8327645 | 0.78 | KMT2A (0.51) | KMT2AMEN1ALDH1A1NPC1KDM4E | |
| SCHEMBL8566663 | 0.78 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL9875559 | 0.78 | KMT2A (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |