Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874641 | 1.00 | SLC6A4 (0.46) | SLC6A4MAPTDRD4DRD2NPC1 | |
| SCHEMBL9872892 | 0.85 | SLC6A4 (0.43) | SLC6A4DRD4DRD2NPC1RAB9A | |
| SCHEMBL9872891 | 0.85 | SLC6A4 (0.43) | SLC6A4DRD4DRD2NPC1RAB9A | |
| SCHEMBL7785539 | 0.77 | CYP1A2 (0.49) | SLC6A4DRD4DRD2ALDH1A1LMNA | |
| SCHEMBL9775143 | 0.77 | ALDH1A1 (0.58) | DRD2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL6814945 | 0.76 | HTR7 (0.53) | SLC6A4DRD4DRD2LMNAGAA | |
| SCHEMBL18601776 | 0.76 | HTR7 (0.53) | SLC6A4DRD4DRD2LMNAGAA | |
| SCHEMBL9872693 | 0.75 | SLC6A4 (0.44) | SLC6A4DRD4DRD2GAA | |
| SCHEMBL9872696 | 0.75 | SLC6A4 (0.44) | SLC6A4DRD4DRD2GAA | |
| SCHEMBL318891 | 0.75 | SLC6A4 (0.51) | SLC6A4DRD4DRD2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039706-A | Antiinflammatory, antiallergenic agent | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-13 | — | — | US | disclosed |