Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 10/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872892 | 1.00 | SLC6A4 (0.43) | SLC6A4DRD4DRD2SMN1; SMN2NPC1 | |
| SCHEMBL9874645 | 0.85 | SLC6A4 (0.46) | SLC6A4DRD4DRD2NPC1RAB9A | |
| SCHEMBL9874641 | 0.85 | SLC6A4 (0.46) | SLC6A4DRD4DRD2NPC1RAB9A | |
| SCHEMBL9775196 | 0.79 | ALDH1A1 (0.53) | DRD4DRD2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18601776 | 0.72 | HTR7 (0.53) | SLC6A4DRD4DRD2SMN1; SMN2PPARG | |
| SCHEMBL6814945 | 0.72 | HTR7 (0.53) | SLC6A4DRD4DRD2SMN1; SMN2PPARG | |
| SCHEMBL9872696 | 0.72 | SLC6A4 (0.44) | SLC6A4DRD4DRD2PPARGPPARA | |
| SCHEMBL9872693 | 0.72 | SLC6A4 (0.44) | SLC6A4DRD4DRD2PPARGPPARA | |
| SCHEMBL318891 | 0.71 | SLC6A4 (0.51) | SLC6A4DRD4DRD2SMN1; SMN2NPC1 | |
| SCHEMBL318549 | 0.71 | SLC6A4 (0.51) | SLC6A4DRD4DRD2SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039706-A | Antiinflammatory, antiallergenic agent | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-13 | — | — | US | disclosed |