Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875654 | 0.85 | RXRA (0.53) | ATML3MBTL1RXRARXRBRXRG | |
| SCHEMBL29359636 | 0.83 | RXRA (0.59) | ATML3MBTL1RXRARXRBRXRG | |
| SCHEMBL13533360 | 0.83 | RXRA (0.59) | ATML3MBTL1RXRARXRBRXRG | |
| SCHEMBL24726655 | 0.81 | AKR1C3 (0.44) | ATML3MBTL1RXRARXRBRXRG | |
| SCHEMBL14707683 | 0.81 | PTGS1 (0.46) | RXRARXRBRXRGPTGS2PTPN5 | |
| SCHEMBL9177215 | 0.81 | RXRA (0.50) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9876212 | 0.79 | PTPN5 (0.44) | L3MBTL1RXRARXRBRXRGPTPN5 | |
| SCHEMBL15340859 | 0.79 | LMNA (0.43) | ATML3MBTL1RXRARXRBRXRG | |
| SCHEMBL9876152 | 0.79 | RXRA (0.46) | RXRARXRBRXRGPTPN5JAK2 | |
| SCHEMBL12570868 | 0.78 | AKR1C3 (0.50) | PTGS2PTGS1LMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |