Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875654 | 0.85 | RXRA (0.53) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL9177215 | 0.85 | RXRA (0.50) | RXRARXRBRXRGLMNAPTPN5 | |
| SCHEMBL9876346 | 0.81 | RXRA (0.45) | RXRARXRBRXRGLMNAPTPN5 | |
| SCHEMBL9875662 | 0.79 | LMNA (0.55) | RXRARXRBRXRGLMNAPTPN5 | |
| SCHEMBL9876129 | 0.79 | CNR2 (0.51) | AKR1C3AKR1C2ENPP3PDK2CNR2 | |
| SCHEMBL6915406 | 0.79 | RXRA (0.53) | RXRARXRBRXRGLMNAJAK2 | |
| SCHEMBL9874684 | 0.79 | ATM (0.44) | RXRARXRBRXRGLMNAJAK2 | |
| SCHEMBL29352930 | 0.78 | ACHE (0.55) | RXRARXRBRXRGLMNAJAK2 | |
| SCHEMBL99347 | 0.78 | ACHE (0.55) | RXRARXRBRXRGLMNAJAK2 | |
| SCHEMBL5490186 | 0.78 | ACHE (0.55) | RXRARXRBRXRGLMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |