Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 6/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506585 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9876497 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9506549 | 0.84 | HDAC3 (0.40) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6152873 | 0.72 | MAOB (0.57) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6152875 | 0.72 | MAOB (0.57) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10949559 | 0.71 | MAP2K7 (0.45) | AURKA | |
| SCHEMBL9474776 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9474772 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16326619 | 0.68 | KDM4E (0.36) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9474666 | 0.67 | CNR1 (0.60) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064723-A | METAL TREATMENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-12 | — | — | US | claimed |