Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 16/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874685 | 0.84 | KDM4E (0.45) | HDAC3KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9506585 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9876497 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9475174 | 0.81 | CNR1 (0.43) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9510451 | 0.80 | HDAC1 (0.41) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9508860 | 0.79 | P2RY12 (0.44) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL11489249 | 0.79 | LMNA (0.52) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11067406 | 0.78 | SMN1; SMN2 (0.53) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2705691 | 0.76 | POLB (0.50) | KMT2AMAPT | |
| SCHEMBL21731447 | 0.76 | HDAC4 (0.64) | HDAC3HDAC1HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285266-B1 | METAL TREATMENT | ZENECA LIMITED (GB) | 1993-08-25 | — | — | EP | claimed |
| EP-0285266-B1 | METAL TREATMENT | ZENECA LIMITED (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5064723-A | METAL TREATMENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-12 | — | — | US | disclosed |