Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873751 | 0.91 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1NPSR1SPHK1SPHK2 | |
| SCHEMBL9873582 | 0.89 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPSR1SPHK1SPHK2 | |
| SCHEMBL9873543 | 0.89 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1NPSR1SPHK1SPHK2 | |
| SCHEMBL9871405 | 0.88 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9873982 | 0.84 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1NPSR1SPHK1SPHK2 | |
| SCHEMBL9874803 | 0.82 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1 | |
| SCHEMBL9873427 | 0.79 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL10775425 | 0.77 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NPSR1CA2CA12 | |
| SCHEMBL21715104 | 0.75 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9871268 | 0.74 | PREP (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |