Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9874813 | 0.76 | MAPK1 (0.46) | MAPK1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26118271 | 0.69 | — | — | |
| SCHEMBL2957850 | 0.69 | MAPK1 (0.54) | MAPK1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7808288 | 0.69 | HSD11B1 (0.45) | MAPK1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL212464 | 0.68 | RAB9A (0.47) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL2957846 | 0.67 | MAPK1 (0.52) | MAPK1CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL7705509 | 0.67 | HSD11B1 (0.44) | MAPK1CHRM2CHRM1CHRM3CHRNA7 | |
| SCHEMBL2045395 | 0.67 | RAB9A (0.38) | MAPK1 | |
| SCHEMBL2046021 | 0.67 | ALDH1A1 (0.32) | MAPK1 | |
| SCHEMBL29721352 | 0.66 | KMT2A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |
| US-4789673-A | ANTISEROTONINE AGENTS | NOVARTIS AG (CH) | 1988-12-06 | — | — | US | disclosed |