Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875180 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHIF1AGAA | |
| SCHEMBL9872741 | 0.85 | GAA (0.47) | ALDH1A1HPGDGAASMN1; SMN2NPSR1 | |
| SCHEMBL9872738 | 0.85 | GAA (0.47) | ALDH1A1HPGDGAASMN1; SMN2NPSR1 | |
| SCHEMBL7269945 | 0.84 | HPGD (0.52) | ALDH1A1HPGDLMNAHIF1AGAA | |
| SCHEMBL9873608 | 0.84 | MEN1 (0.49) | ALDH1A1HPGDLMNAHSD11B1POLB | |
| SCHEMBL9873616 | 0.84 | MEN1 (0.49) | ALDH1A1HPGDLMNAHSD11B1POLB | |
| SCHEMBL9874972 | 0.84 | HSD11B1 (0.47) | ALDH1A1HPGDGAAHSD11B1NPSR1 | |
| SCHEMBL9873876 | 0.84 | HSD11B1 (0.47) | ALDH1A1HPGDGAAHSD11B1NPSR1 | |
| SCHEMBL9872312 | 0.84 | SLC6A1 (0.54) | ALDH1A1HPGDGAAPOLBL3MBTL1 | |
| SCHEMBL9872319 | 0.84 | SLC6A1 (0.54) | ALDH1A1HPGDGAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |