SCHEMBL9875353

SCHEMBL9875353

Cc1ccc2cc3c(c-2cc1)CCCCC3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 3/20 0.37
HSD17B1 P14061 1/20 0.37
ALDH1A1 P00352 3/20 0.35
PTGS2 P35354 1/20 0.35
NLRP3 Q96P20 1/20 0.35
CES1 P23141 1/20 0.35
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9875676 0.98 MEN1 (0.44) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL9876086 0.94 MAPT (0.41) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL9876155 0.81 HPGD (0.40) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL9876360 0.81 HPGD (0.40) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL9876562 0.81 HPGD (0.40) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL9876199 0.79 MEN1 (0.47) MEN1KMT2AMAPTLMNANPC1
SCHEMBL9876382 0.79 LMNA (0.40) MEN1KMT2AMAOAMAOBMAPT
SCHEMBL28180621 0.77 MEN1 (0.49) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL9876227 0.76 MEN1 (0.49) MEN1KMT2AMAPTLMNANPC1
SCHEMBL9875680 0.75 LMNA (0.40) MEN1KMT2AMAOAMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed