SCHEMBL9876562

SCHEMBL9876562

CC(C)c1ccc2cc3c(c-2cc1)CCCCCCCCCC3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.37
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HSD17B1 P14061 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MIF P14174 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
MAPT P10636 1/20 0.32
CYP11B2 P19099 1/20 0.32
XDH P47989 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876360 1.00 HPGD (0.40) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9876155 1.00 HPGD (0.40) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9876382 0.98 LMNA (0.40) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9875680 0.95 LMNA (0.40) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9875353 0.81 MEN1 (0.42) HPGDKDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL9876374 0.81 ALDH1A1 (0.36) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9873863 0.81 ALDH1A1 (0.36) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9876279 0.81 ALDH1A1 (0.36) HPGDKDM4ELMNAALDH1A1ATM
SCHEMBL9875676 0.79 MEN1 (0.44) HPGDKDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL9876322 0.79 LMNA (0.36) HPGDKDM4ELMNAALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed