SCHEMBL9875680

SCHEMBL9875680

CC(C)c1ccc2cc3c(c-2cc1)CCC3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
KDM4E B2RXH2 2/20 0.36
HPGD P15428 3/20 0.35
ALDH1A1 P00352 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B1 P14061 2/20 0.35
XDH P47989 1/20 0.35
SLC22A12 Q96S37 1/20 0.35
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
MIF P14174 1/20 0.34
NISCH Q9Y2I1 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
PRKCI P41743 1/20 0.32
TRPA1 O75762 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876382 0.97 LMNA (0.40) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9876360 0.95 HPGD (0.40) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9876562 0.95 HPGD (0.40) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9876155 0.95 HPGD (0.40) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL24847356 0.81 KDM4E (0.38) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9876086 0.80 MAPT (0.41) LMNAKDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL9875744 0.80 RXRA (0.36) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9876322 0.77 LMNA (0.36) LMNAKDM4EHPGDALDH1A1ATM
SCHEMBL9875676 0.77 MEN1 (0.44) LMNAKDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL9876279 0.76 ALDH1A1 (0.36) LMNAKDM4EHPGDALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed