Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875486 | 0.78 | KMT2A (0.60) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL9874630 | 0.77 | KMT2A (0.50) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL2022576 | 0.68 | KMT2A (0.60) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL10679642 | 0.68 | KDM4E (0.71) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9872808 | 0.67 | KMT2A (0.40) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL8322999 | 0.66 | KMT2A (0.58) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL23144946 | 0.66 | KMT2A (0.57) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL29843236 | 0.66 | KMT2A (0.57) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL12550518 | 0.66 | POLB (0.50) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL8565268 | 0.65 | DPP4 (0.42) | KMT2AMEN1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |