Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.48 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443574 | 0.81 | KCNE1 (0.40) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL9876323 | 0.79 | KCNE1 (0.42) | KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL9876244 | 0.79 | KCNE1 (0.41) | KDM4EKCNE1KCNQ1ABCB1 | |
| SCHEMBL6560807 | 0.78 | KCNE1 (0.78) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL6560803 | 0.78 | KCNE1 (0.78) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL6560812 | 0.78 | KCNE1 (0.78) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL9876223 | 0.76 | ABCC9 (0.58) | ABCB1ABCC9 | |
| SCHEMBL9876547 | 0.76 | ABCC9 (0.51) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL9620896 | 0.76 | KDM4E (0.78) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 | |
| SCHEMBL6559939 | 0.75 | KCNE1 (0.79) | KDM4EKCNE1KCNQ1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |