Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 12/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 12/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876244 | 0.90 | KCNE1 (0.41) | KCNE1KCNQ1KCNH2ABCB1KDM4E | |
| SCHEMBL9875768 | 0.79 | KDM4E (0.58) | KCNE1KCNQ1ABCB1KDM4E | |
| SCHEMBL9787045 | 0.62 | DRD3 (0.53) | ACHE | |
| SCHEMBL9662572 | 0.61 | KDM4E (0.61) | KCNE1KCNQ1ABCB1KDM4E | |
| SCHEMBL9876321 | 0.61 | KCNE1 (0.40) | KCNE1KCNQ1ABCB1KDM4E | |
| SCHEMBL9443574 | 0.61 | KCNE1 (0.40) | KCNE1KCNQ1ABCB1KDM4E | |
| SCHEMBL6935860 | 0.60 | KCNE1 (0.74) | KCNE1KCNQ1KCNH2ABCB1KDM4E | |
| SCHEMBL6935866 | 0.60 | KCNE1 (0.74) | KCNE1KCNQ1KCNH2ABCB1KDM4E | |
| SCHEMBL6935862 | 0.60 | KCNE1 (0.74) | KCNE1KCNQ1KCNH2ABCB1KDM4E | |
| SCHEMBL6938866 | 0.59 | KCNE1 (0.71) | KCNE1KCNQ1KCNH2ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |