Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875571 | 0.74 | POLB (0.37) | POLBHPGDCYP19A1MEN1ALDH1A1 | |
| SCHEMBL7783933 | 0.71 | TSHR (0.58) | POLBHPGDCYP19A1HSP90AA1MEN1 | |
| SCHEMBL9876051 | 0.71 | CYP19A1 (0.40) | CYP19A1HSP90AA1MEN1KMT2A | |
| SCHEMBL13733235 | 0.69 | CYP19A1 (0.49) | CYP19A1HSP90AA1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL5652006 | 0.69 | — | — | |
| SCHEMBL5652011 | 0.69 | — | — | |
| SCHEMBL11188697 | 0.69 | HMOX1 (0.51) | POLBHPGDCYP19A1HDAC1HDAC6 | |
| SCHEMBL9634892 | 0.69 | CYP19A1 (0.50) | POLBHPGDCYP19A1MEN1ALDH1A1 | |
| SCHEMBL11273790 | 0.69 | CYP19A1 (0.59) | POLBHPGDCYP19A1HSP90AA1KMT2A | |
| SCHEMBL6898380 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241232-B1 | ISOXAZOLYLETHANOL DERIVATIVES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-02-27 | — | — | EP | claimed |