Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639867 | 0.84 | GLA (1.00) | GLAHTTLMNATSHRHPGD | |
| SCHEMBL9870534 | 0.77 | PSD (0.62) | LMNATSHRHPGDMAPTSMN1; SMN2 | |
| SCHEMBL14485993 | 0.75 | DAO (0.56) | GLALMNA | |
| SCHEMBL9870574 | 0.70 | GLA (0.61) | GLAHTTLMNATSHRHPGD | |
| SCHEMBL11464707 | 0.69 | CYP2E1 (0.65) | HTTLMNAHPGDMAPTSMN1; SMN2 | |
| SCHEMBL10857521 | 0.69 | KDM4E (0.63) | GLAHTTLMNATSHRHPGD | |
| SCHEMBL22639722 | 0.65 | SMN1; SMN2 (0.62) | HTTLMNATSHRHPGDMAPT | |
| SCHEMBL20828281 | 0.65 | LMNA (0.74) | HTTLMNATSHRMAPTSMN1; SMN2 | |
| SCHEMBL31421768 | 0.65 | — | — | |
| SCHEMBL12596 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |