Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838119 | 0.77 | POLB (0.67) | HTTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL22639867 | 0.76 | GLA (1.00) | GLAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6483534 | 0.72 | RAB9A (0.64) | HTTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9872406 | 0.71 | KMT2A (0.72) | HTTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL9870409 | 0.71 | GPR84 (0.47) | GLAALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9677090 | 0.71 | HRH4 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL9876064 | 0.70 | GLA (0.72) | GLAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9676742 | 0.70 | SMN1; SMN2 (0.48) | HTTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL20828281 | 0.69 | LMNA (0.74) | HTTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9678318 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |