Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872522 | 0.84 | ALDH1A1 (0.62) | PSDALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9876064 | 0.77 | GLA (0.72) | ALDH1A1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL19099442 | 0.77 | PSD (1.00) | PSDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9870231 | 0.75 | LMNA (0.57) | PSDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL18063501 | 0.74 | HPGD (0.73) | ALDH1A1SMN1; SMN2L3MBTL1RAB9ALMNA | |
| SCHEMBL14485993 | 0.74 | DAO (0.56) | LMNA | |
| SCHEMBL11464707 | 0.73 | CYP2E1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1890037 | 0.73 | GPR84 (0.67) | ALDH1A1L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL9879743 | 0.73 | MAPT (0.55) | PSDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL16910517 | 0.71 | L3MBTL1 (0.61) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |