Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31531675 | 0.77 | HTT (0.40) | HTTKDM4EGAA | |
| SCHEMBL9875374 | 0.76 | HTT (0.33) | HTTTP53ALDH1A1MCOLN3KDM4E | |
| SCHEMBL31531684 | 0.74 | HTT (0.40) | HTTKDM4EGAA | |
| SCHEMBL31040271 | 0.74 | HTT (0.36) | HTTALDH1A1 | |
| SCHEMBL3747956 | 0.73 | UGT2B7 (0.39) | — | |
| SCHEMBL9951819 | 0.72 | HTT (0.41) | HTTKDM4EGAA | |
| SCHEMBL4828602 | 0.72 | IDO1 (0.37) | HTTALDH1A1GAA | |
| SCHEMBL30871737 | 0.71 | HTT (0.35) | HTTKDM4EGAA | |
| SCHEMBL14454024 | 0.71 | — | — | |
| SCHEMBL9876018 | 0.70 | ALPL (0.41) | TP53ALDH1A1MCOLN3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |