Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676163 | 0.82 | LMNA (0.77) | LMNAPTGS1TRPA1CACNA1CAKR1C3 | |
| SCHEMBL2581740 | 0.80 | LMNA (0.67) | LMNAPTGS1TRPA1CACNA1CHDAC4 | |
| SCHEMBL10416092 | 0.78 | LMNA (0.86) | LMNAPTGS1TRPA1CACNA1CAKR1C3 | |
| SCHEMBL24102178 | 0.75 | LMNA (0.65) | LMNAPTGS1TRPA1CACNA1CAKR1C3 | |
| SCHEMBL16852245 | 0.73 | AKR1C3 (0.69) | LMNAAKR1C3AKR1C2HDAC4HDAC8 | |
| SCHEMBL30865662 | 0.73 | LMNA (0.47) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL29831674 | 0.73 | CYP1A2 (0.54) | LMNAPTGS1TRPA1CACNA1CHDAC4 | |
| SCHEMBL11449736 | 0.73 | LMNA (0.44) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL5027898 | 0.73 | ACHE (0.47) | ALDH1A1TP53TDP1ACHEPDK2 | |
| SCHEMBL28503898 | 0.72 | LMNA (0.50) | LMNAPTGS1TRPA1CACNA1CMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |