SCHEMBL2581740

SCHEMBL2581740

Cc1cccc(C)c2cc(C(C)C)cc1-2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
PTGS1 P23219 2/20 0.46
TRPA1 O75762 1/20 0.46
CACNA1C Q13936 1/20 0.46
ALDH1A1 P00352 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2A6 P11509 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MDM4 O15151 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
TYR P14679 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31051327 0.84 LMNA (0.90) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL9876237 0.80 LMNA (0.54) LMNAPTGS1TRPA1CACNA1CALDH1A1
Guaiazulen SCHEMBL29259925 0.80 LMNA (1.00) LMNAPTGS1TRPA1CACNA1CALDH1A1
Guaiazulen SCHEMBL26982 0.80 LMNA (1.00) LMNAPTGS1TRPA1CACNA1CALDH1A1
Guaiazulen SCHEMBL29639620 0.80 LMNA (1.00) LMNAPTGS1TRPA1CACNA1CALDH1A1
Guaiazulen SCHEMBL7916824 0.78 LMNA (0.95) LMNAPTGS1TRPA1CACNA1CALDH1A1
Guaiazulen SCHEMBL27806695 0.78 LMNA (0.95) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL8850182 0.78 LMNA (0.57) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL30865662 0.78 LMNA (0.47) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL9875662 0.76 LMNA (0.55) LMNAPTGS1TRPA1CACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655386-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS Fertis India Pvt Ltd (IN) 2025-12-03 EP claimed
US-20250248400-A1 NANOPARTICULATE FORMULATION FOR PREVENTING OR TREATING CALLOSE FORMATION IN PLANTS PURDUE RESEARCH FOUNDATION (US) 2025-08-07 US claimed
WO-2024121870-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS FERTIS INDIA PVT. LTD. (IN) 2024-06-13 WO claimed
US-20230380428-A1 BIODEGRADABLE CLEANING PRODUCTS, METHODS OF PRODUCTION, AND THEIR COMPOSITIONS SUSTAINABLE COMMUNITY DEV LLC (US) 2023-11-30 US claimed
WO-2022081174-A1 BIODEGRADABLE CLEANING PRODUCTS, METHODS OF PRODUCTION, AND THEIR COMPOSITIONS SUSTAINABLE COMMUNITY DEVELOPMENT, LLC (US) 2022-04-21 WO claimed
US-20190224193-A1 Compositions of Natural Extracts and Use Thereof in Methods for Preventing or Treating Diseases REID CHRISTOPHER BRIAN (US) 2019-07-25 US claimed
WO-2018111194-A1 TARGETS FOR IMPROVING TERPENE PRODUCTION IN RHODOSPORIDIUM TORULOIDES TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2018-06-21 WO claimed
WO-2017161387-A1 COMPOSITIONS OF NATURAL EXTRACTS AND USE THEREOF IN METHODS FOR PREVENTING OR TREATING DISEASES REID CHRISTOPHER BRIAN (US) 2017-09-21 WO claimed
US-20140271923-A1 Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions REID CHRISTOPHER BRIAN (US) 2014-09-18 US claimed
WO-2007066305-A1 COMPOSITIONS COMPRISING SESQUITERPENE COMPOUNDS FOR USE IN THE PROPHYLAXIS OR TREATMENT OF PAIN ZELPY 2549 (PTY) LIMITED (ZA) 2007-06-14 WO claimed
US-20260041726-A1 OIL EXTRACT OF CANNABIS AND METHOD FOR OBTAINING CONCEPT MATRIX SOLUTIONS (US) 2026-02-12 US disclosed
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2026-02-05 US disclosed
US-20260027136-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE YUZU LV LLC (US) 2026-01-29 US disclosed
US-20250369022-A1 PRODUCTION OF NATURAL GUM BASE INGREDIENTS BY PLANT CELL FERMENTATION AND APPLICATION THEREOF IN CONFECTIONERY WM. WRIGLEY JR. COMPANY (US) 2025-12-04 US disclosed
EP-4655386-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS Fertis India Pvt Ltd (IN) 2025-12-03 EP disclosed
WO-2005013931-A1 USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 WO disclosed
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 US disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 US disclosed
US-6069113-A GIVEN AMOUNT OF TERPENE, AN EMULSIFIER COMPRISING THE REACTION PRODUCT OF A TALL OIL FATTY ACID AND AN ALCOHOL AMINE, AND A COPPER COMPLEX; LESS TOXIC AND LESS FLAMMABLE LAPORTE WATER TECHNOLOGIES & BIOCHEM, INC. (US) 2000-05-30 US disclosed
US-5112358-A Terpene Solvents PARADIGM TECHNOLOGY CO., INC. (US) 1992-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041726-A1 OIL EXTRACT OF CANNABIS AND METHOD FOR OBTAINING NAPEPLD, CNR2, PRKCE LMNA 2580/4885PTGS1 1525/4885TRPA1 1996/4885
US-20260027136-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE CNR1, CNR2, OPRM1 LMNA 293/4885PTGS1 205/4885TRPA1 365/4885
US-20260034186-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS TRPV1, SOST, RUNX1 LMNA 3179/4885PTGS1 1738/4885TRPA1 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.