Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450446 | 0.79 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2GAAGFER | |
| SCHEMBL156842 | 0.74 | CHRNB2 (0.56) | ALDH1A1KDM4ESMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL8089772 | 0.71 | GFER (0.52) | ALDH1A1SMN1; SMN2GAAGFERMAPT | |
| SCHEMBL8096935 | 0.71 | GFER (0.52) | ALDH1A1KDM4ESMN1; SMN2GAAGFER | |
| SCHEMBL8089828 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2GAAGFERMAPT | |
| SCHEMBL9871142 | 0.71 | RAB9A (0.46) | ALDH1A1KDM4EGAACHRNB2CHRNA4 | |
| SCHEMBL8099174 | 0.71 | GFER (0.52) | ALDH1A1KDM4ESMN1; SMN2GAAGFER | |
| SCHEMBL8089821 | 0.71 | GFER (0.56) | SMN1; SMN2GAAGFERL3MBTL1TDP1 | |
| SCHEMBL2788897 | 0.70 | CHRNB2 (0.56) | KDM4ESMN1; SMN2GAACHRNB2CHRNA4 | |
| SCHEMBL8923934 | 0.70 | CHRNB2 (0.56) | ALDH1A1KDM4ESMN1; SMN2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1341594-A | Substituted pyrrolidone, thiazolidone or oxazolidone as herbicide | ZENECA LTD (GB) | 2002-03-27 | — | — | CN | disclosed |
| CN-1153512-A | Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides | ZENECA LTD (GB) | 1997-07-02 | — | — | CN | disclosed |
| US-5021435-A | Administering to a patient suffering from an ulcer caused by stress or gastric acid | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |