Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9819793 | 0.90 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7MAPTCYP2A6 | |
| SCHEMBL4153725 | 0.78 | MAPT (0.61) | CHRNB2CHRNA4CHRNA7MAPTSMN1; SMN2 | |
| Heptylformamide SCHEMBL9819900 | 0.78 | MAPT (0.43) | CHRNB2CHRNA4CHRNA7MAPTALDH1A1 | |
| SCHEMBL4655299 | 0.77 | MAPT (0.66) | MAPTSMN1; SMN2CYP2D6CYP2C19TDP1 | |
| SCHEMBL2335474 | 0.75 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CYP2A6SMN1; SMN2 | |
| SCHEMBL9370773 | 0.72 | KDM4E (0.50) | CHRNB2CHRNA4CHRNA7CYP2A6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2436158 | 0.72 | MAOA (0.48) | CHRNB2CHRNA4CHRNA7CYP2A6SMN1; SMN2 | |
| SCHEMBL159642 | 0.72 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CYP2A6SMN1; SMN2 | |
| Bicarbonate SCHEMBL9826841 | 0.71 | MAPT (0.58) | MAPTSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL27467551 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | claimed |
| JP-9249565-A | — | — | None | — | — | JP | disclosed |
| JP-5051381-A | — | — | None | — | — | JP | disclosed |
| CN-1265648-A | Conjugaes of dithiocarbamates with pharmacologically active agents and uses therefor | MEDINOX INC (US) | 2000-09-06 | — | — | CN | disclosed |
| JP-H09249565-A | THIAZOLIDINE HAVING ANTI-HIV ACTIVITY | NIPPON SUISAN KAISHA LTD | 1997-09-22 | — | — | JP | disclosed |
| JP-H0551381-A | THIAZOLIDINE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1993-03-02 | — | — | JP | disclosed |
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |