Dcmu

Dcmu

SCHEMBL9876296

CCCC(=O)Oc1c(Br)cc(C#N)cc1Br.CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1.Nc1nc[nH]n1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.41
KMT2A Q03164 6/20 0.36
MEN1 O00255 4/20 0.36
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
LMNA P02545 2/20 0.35
GLA P06280 2/20 0.33
MAPT P10636 1/20 0.33
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.30
MCHR1 Q99705 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dcmu SCHEMBL9876450 0.93 APEX1 (0.35) APEX1KMT2AMEN1ALDH1A1HPGD
Atrazine SCHEMBL9876705 0.89 MAPT (0.33) APEX1KMT2AALDH1A1LMNAMAPT
Dcmu SCHEMBL9876837 0.82 APEX1 (0.42) APEX1KMT2AMEN1ALDH1A1HPGD
Atrazine SCHEMBL9876366 0.78 APEX1 (0.38) APEX1KMT2AMEN1ALDH1A1HPGD
Simazine SCHEMBL9876727 0.78 LMNA (0.32) LMNAHTTKDM4EGAA
Atrazine SCHEMBL9876340 0.73 ALDH1A1 (0.39) KMT2AALDH1A1LMNAMAPTHTT
Linuron SCHEMBL11037224 0.72 KMT2A (0.57) APEX1KMT2AMEN1ALDH1A1HPGD
SCHEMBL163129 0.70 AKR1B1 (0.42) KMT2AMEN1ALDH1A1
Bromoxynil SCHEMBL28163651 0.66 TTR (0.53) KMT2AMEN1TSHR
Dcmu SCHEMBL28964105 0.66 APEX1 (0.96) APEX1KMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021083-A Stable aqueous or aqueous alcoholic dispersion based on derivatives of oxynil, herbicidal composition comprised thereof and selective herbicidal treatment comprising the use of the said herbicidal composition COMPAGNIE FRANCAISE DE PRODUITS INDUSTRIELS (FR) 1991-06-04 US disclosed