Dcmu

Dcmu

SCHEMBL9876837

CCCC(=O)Oc1c(Br)cc(C#N)cc1Br.CCNc1nc(Cl)nc(NCC)n1.CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.42
MAPT P10636 4/20 0.40
KMT2A Q03164 7/20 0.35
MEN1 O00255 6/20 0.35
ALDH1A1 P00352 6/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Atrazine SCHEMBL9876366 0.95 APEX1 (0.38) APEX1MAPTKMT2AMEN1ALDH1A1
Dcmu SCHEMBL9876450 0.92 APEX1 (0.35) APEX1MAPTKMT2AMEN1ALDH1A1
Atrazine SCHEMBL9876705 0.88 MAPT (0.33) APEX1MAPTKMT2AALDH1A1LMNA
Simazine SCHEMBL9876438 0.86 LMNA (0.40) MAPTKMT2AMEN1ALDH1A1LMNA
Dcmu SCHEMBL9876296 0.82 APEX1 (0.41) APEX1MAPTKMT2AMEN1ALDH1A1
Dcmu SCHEMBL8736974 0.80 APEX1 (0.66) APEX1MAPTKMT2AMEN1ALDH1A1
Atrazine SCHEMBL9876273 0.80 ALDH1A1 (0.43) MAPTKMT2AALDH1A1LMNAHTT
Simazine SCHEMBL9876727 0.77 LMNA (0.32) LMNAHTTKDM4EPKMGAA
Atrazine SCHEMBL9983133 0.74 APEX1 (0.56) APEX1MAPTKMT2AMEN1LMNA
Atrazine SCHEMBL9876340 0.72 ALDH1A1 (0.39) MAPTKMT2AALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021083-A Stable aqueous or aqueous alcoholic dispersion based on derivatives of oxynil, herbicidal composition comprised thereof and selective herbicidal treatment comprising the use of the said herbicidal composition COMPAGNIE FRANCAISE DE PRODUITS INDUSTRIELS (FR) 1991-06-04 US disclosed