Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877691 | 0.91 | CCNA2 (0.39) | CCNA2CDK2PDE4AKCNH2MEN1 | |
| SCHEMBL9877012 | 0.91 | CCNA2 (0.39) | CCNA2CDK2PDE4AKCNH2MEN1 | |
| SCHEMBL9876520 | 0.88 | PTGER1 (0.38) | PTGER1GBA1CCNA2CDK2PDE4A | |
| SCHEMBL9234476 | 0.83 | TNK2 (0.44) | PTGER1CCNA2CDK2 | |
| SCHEMBL9877014 | 0.83 | PTGER1 (0.41) | PTGER1GBA1CCNA2CDK2PDE4A | |
| Fumaric Acid SCHEMBL9237819 | 0.82 | PTGER1 (0.40) | PTGER1CCNA2CDK2PDE4AKCNH2 | |
| Maleic Acid SCHEMBL9237812 | 0.82 | PTGER1 (0.40) | PTGER1CCNA2CDK2PDE4AKCNH2 | |
| SCHEMBL9876903 | 0.81 | CCNA2 (0.53) | PTGER1CCNA2CDK2MAPK1TSHR | |
| SCHEMBL9876945 | 0.80 | CCNA2 (0.37) | CCNA2CDK2PDE4AKCNH2MEN1 | |
| SCHEMBL9876885 | 0.80 | CCNA2 (0.37) | CCNA2CDK2PDE4AKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |