⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299561 | 0.66 | POLB (0.62) | — | |
| SCHEMBL13165565 | 0.66 | POLB (0.50) | — | |
| SCHEMBL61337 | 0.63 | — | — | |
| SCHEMBL23631838 | 0.62 | LMNA (0.44) | — | |
| SCHEMBL2441910 | 0.62 | — | — | |
| SCHEMBL6621934 | 0.61 | — | — | |
| SCHEMBL19520849 | 0.61 | — | — | |
| SCHEMBL4552543 | 0.61 | L3MBTL1 (0.59) | — | |
| SCHEMBL6172380 | 0.61 | L3MBTL1 (0.43) | — | |
| SCHEMBL13165580 | 0.61 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988706-A | Treatment of dementia in mammals, central nervous system disorders, cognition activators | BEECHAM GROUP P.L.C. (GB) | 1991-01-29 | — | — | US | disclosed |
| EP-0339834-A2 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1989-11-02 | — | — | EP | disclosed |