⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010097 | 0.71 | — | — | |
| SCHEMBL9143751 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL461605 | 0.66 | — | — | |
| SCHEMBL9231897 | 0.64 | CSNK2A1 (0.30) | — | |
| SCHEMBL9124197 | 0.64 | — | — | |
| SCHEMBL4422176 | 0.64 | — | — | |
| Bromide SCHEMBL19681460 | 0.64 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL1590395 | 0.62 | — | — | |
| SCHEMBL6845014 | 0.62 | — | — | |
| SCHEMBL643262 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066799-A | Intermediates for the preparation of aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
| US-5066799-A | Intermediates for the preparation of aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
| US-5066799-A | Intermediates for the preparation of aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |