SCHEMBL9143751

SCHEMBL9143751

CC(=O)Oc1nc(N)cs1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX5 P09917 1/20 0.32
LMNA P02545 1/20 0.31
CA2 P00918 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRB2 P47870 1/20 0.31
CYP19A1 P11511 1/20 0.30
TMIGD3 P0DMS9 1/20 0.30
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1000856 0.73 ALDH1A1 (0.44) MEN1ALDH1A1MAPTKMT2AATP4A
SCHEMBL28062242 0.73 GRM5 (0.31) RAB9AHSD17B10
SCHEMBL1415491 0.73 KDM4E (0.33) MAPTHSD17B10KDM4E
SCHEMBL17680549 0.73
Hydrochloric Acid SCHEMBL11102564 0.72 ALDH1A1 (0.46) MEN1ALDH1A1MAPTKMT2AATP4A
SCHEMBL10866605 0.69
SCHEMBL27461331 0.69 RAB9A (0.59) MEN1ALDH1A1MAPTKMT2ANPC1
SCHEMBL9876560 0.69
SCHEMBL8010097 0.68
SCHEMBL9124197 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5464829-A Cephalosporin derivatives MEIJI SEIKA KAISHA LTD. (JP) 1995-11-07 US disclosed
EP-0605836-A1 Cephalosporin derivatives MEIJI SEIKA KAISHA LTD. (JP) 1994-07-13 EP disclosed