Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CCND2 | P30279 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950748 | 0.73 | PTGER3 (0.45) | CDK4CCND1CCND2CCND3CYP1A2 | |
| SCHEMBL3526368 | 0.73 | PKM (0.49) | PKMCYP1A2TSHRALDH1A1CYP3A4 | |
| SCHEMBL23141918 | 0.71 | CDK4 (0.60) | CDK4CCND1CCND2CCND3CYP1A2 | |
| SCHEMBL30718958 | 0.71 | CDK4 (0.60) | CDK4CCND1CCND2CCND3CYP1A2 | |
| SCHEMBL5265127 | 0.71 | MAPK14 (0.58) | PKMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL23142071 | 0.70 | CDK4 (0.59) | CDK4CCND1CCND2CCND3CYP1A2 | |
| SCHEMBL5264386 | 0.70 | CDK4 (1.00) | CDK4CCND1CCND2CCND3CYP1A2 | |
| SCHEMBL23620191 | 0.70 | CYP2C19 (0.56) | PKMTSHRALDH1A1CYP2C19HPGD | |
| SCHEMBL2524154 | 0.70 | L3MBTL1 (0.52) | PKMCYP1A2TSHRCYP2C19MAPK1 | |
| SCHEMBL16253509 | 0.69 | ALDH1A1 (0.46) | PKMCYP1A2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037826-A | Antiallergy, antiulcer, antiinflammatory, skin disorders, immune suppressants | SCHERING CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4916131-A | IMMUNOSUPPRESSANT | SCHERING CORPORATION (US) | 1990-04-10 | — | — | US | disclosed |
| US-4775686-A | Naphthyridine derivatives and method for treating allergic reactions | SCHERING CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |