Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236664 | 0.93 | KDM4E (0.43) | LSSLTA4HGSK3BKDM4ETSHR | |
| SCHEMBL9234584 | 0.90 | LSS (0.46) | LSSLTA4HGSK3BKDM4EHSD17B10 | |
| SCHEMBL9876908 | 0.89 | ALDH1A1 (0.51) | LSSLTA4HGSK3BKDM4EALDH1A1 | |
| SCHEMBL9234490 | 0.89 | GSK3B (0.50) | LSSGSK3BKDM4EALDH1A1KDR | |
| SCHEMBL9876938 | 0.88 | LSS (0.45) | LSSGSK3BKDM4EALDH1A1KDR | |
| SCHEMBL9876682 | 0.87 | GSK3B (0.43) | LSSGSK3BKDM4EALDH1A1KDR | |
| Fumaric Acid SCHEMBL9232176 | 0.86 | GSK3B (0.42) | LSSGSK3BKDM4EALDH1A1KDR | |
| SCHEMBL9237569 | 0.86 | GSK3B (0.42) | LSSLTA4HGSK3BKDM4ETSHR | |
| Maleic Acid SCHEMBL9232171 | 0.86 | GSK3B (0.42) | LSSGSK3BKDM4EALDH1A1KDR | |
| SCHEMBL9876697 | 0.86 | LSS (0.43) | LSSLTA4HGSK3BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |