Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9236893 | 0.92 | LSS (0.45) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fumaric Acid SCHEMBL9236898 | 0.92 | LSS (0.45) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876652 | 0.92 | LSS (0.44) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876899 | 0.91 | CXCR1 (0.45) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876756 | 0.91 | LSS (0.43) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9876810 | 0.90 | TNK2 (0.46) | LSSCYP1A2CYP2D6CYP2C9CYP2C19 | |
| Maleic Acid SCHEMBL9237511 | 0.90 | BCHE (0.44) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fumaric Acid SCHEMBL9237516 | 0.90 | BCHE (0.44) | LSSCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fumaric Acid SCHEMBL9231005 | 0.88 | LSS (0.45) | LSSPSMB5PSMB1CCNA2CDK2 | |
| Maleic Acid SCHEMBL9230995 | 0.88 | LSS (0.45) | LSSPSMB5PSMB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |