Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876909 | 0.95 | LSS (0.44) | GSK3BFGFR1SRCCYP1A2CYP2D6 | |
| SCHEMBL9234476 | 0.94 | TNK2 (0.44) | GSK3BTNK2CHRNB2CHRNA4FGFR1 | |
| SCHEMBL9876897 | 0.93 | KDM4E (0.42) | GSK3BTNK2CHRNB2CHRNA4FGFR1 | |
| Fumaric Acid SCHEMBL9233745 | 0.92 | BTK (0.42) | GSK3BTNK2CHRNB2CHRNA4FGFR1 | |
| Fumaric Acid SCHEMBL9233740 | 0.92 | BTK (0.42) | GSK3BTNK2CHRNB2CHRNA4FGFR1 | |
| SCHEMBL9876810 | 0.91 | TNK2 (0.46) | TNK2CHRNB2CHRNA4FGFR1SRC | |
| SCHEMBL10591505 | 0.89 | TNK2 (0.39) | GSK3BTNK2CHRNB2CHRNA4FGFR1 | |
| SCHEMBL9231684 | 0.88 | ALOX5 (0.42) | FGFR1SRCCYP2D6CYP2C9 | |
| SCHEMBL9876856 | 0.88 | KDM4E (0.43) | FGFR1SRCCYP2D6CYP2C9 | |
| SCHEMBL9235049 | 0.88 | LSS (0.42) | TNK2FGFR1SRCCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |