SCHEMBL9876868

SCHEMBL9876868

CNC#CC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.37
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414348 0.80 DGAT1 (0.40) DGAT1CTSK
SCHEMBL2946741 0.76 DGAT1 (0.44) DGAT1CTSK
SCHEMBL16885807 0.75 DGAT1 (0.37) DGAT1CTSK
SCHEMBL23000955 0.75
SCHEMBL3489322 0.73 DGAT1 (0.36) DGAT1CTSK
SCHEMBL19216979 0.73 DGAT1 (0.36) DGAT1CTSK
SCHEMBL1088416 0.73 CTSK (0.38) DGAT1CTSK
SCHEMBL19912070 0.71 DGAT1 (0.34) DGAT1CTSK
SCHEMBL20657046 0.71 DGAT1 (0.34) DGAT1CTSK
SCHEMBL18186430 0.71 DGAT1 (0.34) DGAT1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3504210-B1 7-SUBSTITUTED SULFONIMIDOYLPURINONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION HOFFMANN LA ROCHE (CH) 2021-02-24 EP claimed
US-5011938-A Antimicrobials ELI LILLY AND COMPANY (US) 1991-04-30 US disclosed
US-4940718-A BACTERICIDES ELI LILLY AND COMPANY (US) 1990-07-10 US disclosed
EP-0202046-A1 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-20 EP disclosed