Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876856 | 0.95 | KDM4E (0.43) | KDM4ECCNA2CDK2GAANPSR1 | |
| SCHEMBL9877072 | 0.93 | GSK3B (0.43) | CHRNB2CHRNA4TNK2GSK3BFGFR1 | |
| Fumaric Acid SCHEMBL9236149 | 0.92 | KDM4E (0.45) | KDM4ECCNA2CDK2CHRNB2CHRNA4 | |
| Maleic Acid SCHEMBL9236144 | 0.92 | KDM4E (0.45) | KDM4ECCNA2CDK2CHRNB2CHRNA4 | |
| SCHEMBL9234476 | 0.91 | TNK2 (0.44) | KDM4ECCNA2CDK2CHRNB2CHRNA4 | |
| SCHEMBL9876909 | 0.88 | LSS (0.44) | KDM4EGSK3BFGFR1SRCSMN1; SMN2 | |
| Fumaric Acid SCHEMBL9234458 | 0.88 | KDM4E (0.46) | KDM4ECCNA2CDK2GAANPSR1 | |
| Fumaric Acid SCHEMBL9234452 | 0.88 | KDM4E (0.46) | KDM4ECCNA2CDK2GAANPSR1 | |
| SCHEMBL9231684 | 0.85 | ALOX5 (0.42) | KDM4ECCNA2CDK2GAAPOLB | |
| Fumaric Acid SCHEMBL9233740 | 0.85 | BTK (0.42) | KDM4ECHRNB2CHRNA4TNK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |