Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877072 | 0.95 | GSK3B (0.43) | FGFR1SRCCYP2D6CYP2C9CYP1A2 | |
| SCHEMBL9235049 | 0.93 | LSS (0.42) | LSSFGFR1SRCCYP3A4CYP2D6 | |
| SCHEMBL9876856 | 0.93 | KDM4E (0.43) | LSSFGFR1SRCCYP3A4CYP2D6 | |
| SCHEMBL9231684 | 0.93 | ALOX5 (0.42) | LSSFGFR1SRCCYP3A4CYP2D6 | |
| Fumaric Acid SCHEMBL9234624 | 0.92 | LSS (0.43) | LSSFGFR1SRCCYP3A4CYP2D6 | |
| Fumaric Acid SCHEMBL9234618 | 0.92 | LSS (0.43) | LSSFGFR1SRCCYP3A4CYP2D6 | |
| SCHEMBL9234476 | 0.88 | TNK2 (0.44) | FGFR1SRCKDM4EALDH1A1GSK3B | |
| SCHEMBL9876897 | 0.88 | KDM4E (0.42) | FGFR1SRCKDM4ESMN1; SMN2GSK3B | |
| SCHEMBL9876652 | 0.88 | LSS (0.44) | LSSCYP3A4CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL9876882 | 0.87 | LSS (0.52) | LSSFGFR1SRCCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |