Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869500 | 0.82 | MAPT (0.54) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL105461 | 0.73 | L3MBTL1 (1.00) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL29624594 | 0.73 | L3MBTL1 (1.00) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6865586 | 0.71 | L3MBTL1 (0.97) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL31157828 | 0.71 | L3MBTL1 (0.97) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL3280776 | 0.71 | KDM4E (0.36) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL10712365 | 0.70 | MAPT (0.38) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL25197773 | 0.69 | KDM4A (0.51) | MAPTTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12834067 | 0.68 | KDM4E (0.40) | MAPTTDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL13222949 | 0.68 | MAPT (0.38) | MAPTTDP1NPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| US-4624977-A | NATURAL OR SYNTHETIC RUBBER DENATURED NITROSOQUINOLINE, CARBON BLACK | BRIDGESTONE CORPORATION (JP) | 1986-11-25 | — | — | US | disclosed |