SCHEMBL105461

SCHEMBL105461

O=Nc1ccc(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 1.00
KDM4E B2RXH2 7/20 1.00
NPC1 O15118 6/20 1.00
MAPT P10636 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
RAB9A P51151 4/20 1.00
ALDH1A1 P00352 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
XBP1 P17861 1/20 1.00
GLO1 Q04760 3/20 0.62
MEN1 O00255 8/20 0.59
KMT2A Q03164 8/20 0.59
HTT P42858 5/20 0.59
LMNA P02545 4/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
MAPK1 P28482 2/20 0.59
OPRK1 P41145 1/20 0.59
KCNH2 Q12809 1/20 0.57
RPS6KA3 P51812 1/20 0.57
HSP90AA1 P07900 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624594 1.00 L3MBTL1 (1.00) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL31157828 0.98 L3MBTL1 (0.97) L3MBTL1KDM4ENPC1MAPTTDP1
Hydrochloric Acid SCHEMBL6865586 0.98 L3MBTL1 (0.97) L3MBTL1KDM4ENPC1MAPTTDP1
Quinoline SCHEMBL28212331 0.88 L3MBTL1 (0.78) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL14424703 0.86 L3MBTL1 (0.75) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL3304702 0.82 MAPT (0.70) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL6709708 0.82 MAPT (0.70) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL5851384 0.79 GLO1 (0.88) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL5851373 0.79 GLO1 (0.88) L3MBTL1KDM4ENPC1MAPTTDP1
SCHEMBL24969543 0.79 MAPT (0.65) L3MBTL1KDM4ENPC1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119753685-A Copper alloy film etching liquid composition 晶瑞电子材料股份有限公司 2025-04-04 CN claimed
CN-118915391-B Photosensitive resin composition containing nitrogen heterocyclic polysiloxane and application thereof 波米科技有限公司 2025-04-01 CN claimed
CN-118915391-A Photosensitive resin composition containing nitrogen heterocyclic polysiloxane and application thereof 波米科技有限公司 2024-11-08 CN claimed
CN-118667162-A Photosensitive polyamic acid ester, preparation method thereof, photosensitive polyimide photoetching composition and application 广东粤港澳大湾区黄埔材料研究院 2024-09-20 CN claimed
CN-117701233-B Photosensitive polyimide glue solution suitable for coating and coating method thereof 明士(北京)新材料开发有限公司 2024-08-02 CN claimed
CN-117186403-B Negative photosensitive resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2024-04-02 CN claimed
CN-117430812-B Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-03-19 CN claimed
CN-117701233-A Photosensitive polyimide glue solution suitable for coating and coating method thereof 明士(北京)新材料开发有限公司 2024-03-15 CN claimed
CN-116841122-B Photosensitive resin composition and preparation method and application thereof 波米科技有限公司 2024-01-30 CN claimed
CN-117210141-B Development-resistant photosensitive adhesive film and preparation and application thereof 明士(北京)新材料开发有限公司 2024-01-26 CN claimed
US-20150148292-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO UNIV EMORY (US) 2015-05-28 US claimed
WO-2014011540-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO EMORY UNIVERSITY (US) 2014-01-16 WO claimed
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO claimed
WO-2001003661-A1 AGENT FOR DYEING KERATIN FIBRES CONTAINING AT LEAST ONE AROMATIC NITROSO COMPOUND HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-18 WO claimed
EP-0943032-B1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN OR LIGNIN-CONTAINING MATERIALS, AND PROCESS FOR USING THE SAME CONSORTIUM ELEKTROCHEM IND (DE) 2000-09-13 EP claimed
CN-1240008-A Multicomponent system for modifying, degrading or bleaching lignin, lignin-containing materials or the like and method for the use thereof ELEKTOCHEMISCHE IND GMBH (DE) 1999-12-29 CN claimed
EP-0943032-A1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME Consortium für elektrochemische Industrie GmbH (DE) 1999-09-22 EP claimed
WO-1998026127-A1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME Consortium für elektrochemische Industrie GmbH (DE) 1998-06-18 WO claimed
US-4624977-A NATURAL OR SYNTHETIC RUBBER DENATURED NITROSOQUINOLINE, CARBON BLACK BRIDGESTONE CORPORATION (JP) 1986-11-25 US claimed
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148292-A1 BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO BMP4, BMP2, BMP1 L3MBTL1 2574/4885KDM4E 1908/4885NPC1 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.