Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726937 | 0.89 | TRPM8 (0.58) | TRPM8SGMS2NPC1HTTGAA | |
| SCHEMBL7866995 | 0.87 | SGMS2 (0.59) | TRPM8SGMS2NPC1HTTGAA | |
| SCHEMBL8775174 | 0.85 | KMT2A (0.61) | TRPM8SGMS2NPC1HTTGAA | |
| SCHEMBL2290346 | 0.85 | TRPM8 (0.55) | TRPM8SGMS2NPC1HTTGAA | |
| SCHEMBL112903 | 0.83 | SGMS2 (0.66) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL29433417 | 0.83 | SGMS2 (0.66) | SGMS2NPC1HTTGAAPTGER1 | |
| Bicarbonate SCHEMBL236872 | 0.82 | SGMS2 (0.64) | SGMS2NPC1HTTGAAPTGER1 | |
| Bicarbonate SCHEMBL21753662 | 0.82 | SGMS2 (0.64) | SGMS2NPC1HTTGAAPTGER1 | |
| Bicarbonate SCHEMBL29914194 | 0.82 | SGMS2 (0.64) | SGMS2NPC1HTTGAAPTGER1 | |
| Hydrochloric Acid SCHEMBL8998291 | 0.82 | SGMS2 (0.64) | SGMS2NPC1HTTGAAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036157-A | Hydroxamic acid derivatives, lipoxygenase and cyclooxygenase inhibitors, anticoagulants, antiinflammatory agents | BURROUGHS WELLCOME CO. | 1991-07-30 | — | — | US | disclosed |
| US-4977188-A | Hydroamic acid derivatives | BURROUGHS WELLCOME CO. (US) | 1990-12-11 | — | — | US | disclosed |
| WO-1990001929-A1 | NEW MEDICAL USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-03-08 | — | — | WO | disclosed |
| US-4738986-A | CYCLOOXYGENASE, LIDOXYGENASE INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | disclosed |