Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877332 | 0.78 | MAPT (0.54) | MAPTTP53ALDH1A1KDM4EHTT | |
| SCHEMBL9876957 | 0.78 | GFER (0.42) | GFERMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL9877360 | 0.77 | SMN1; SMN2 (0.65) | GFERMAPTALDH1A1KDM4EHTT | |
| SCHEMBL8765117 | 0.69 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHTTPOLB | |
| SCHEMBL28101559 | 0.68 | ALDH1A1 (0.44) | MAPTTP53ALDH1A1KDM4EHTT | |
| SCHEMBL9828305 | 0.67 | MAPT (0.41) | MAPTTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL9877095 | 0.67 | SMN1; SMN2 (0.76) | MAPTALDH1A1KDM4EHTTPOLB | |
| SCHEMBL9877609 | 0.67 | SMN1; SMN2 (0.51) | MAPTTP53ALDH1A1KDM4EHTT | |
| SCHEMBL5062856 | 0.65 | ALDH1A1 (0.67) | MAPTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL9877279 | 0.65 | SMN1; SMN2 (0.68) | MAPTALDH1A1KDM4EHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988725-A | Cardiovascular disorders, antiarrhythmia agents | STERLING DRUG INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0388654-A2 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4916150-A | 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use | STERLING DRUG INC. (US) | 1990-04-10 | — | — | US | disclosed |