Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877007 | 0.78 | GFER (0.50) | GFERALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL9877727 | 0.75 | GFER (0.37) | GFERALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL9877815 | 0.71 | NPC1 (0.41) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL9877735 | 0.70 | PTGIR (0.48) | ALDH1A1SMN1; SMN2NPSR1TP53RAB9A | |
| SCHEMBL9877992 | 0.66 | MAPK1 (0.51) | GFERALDH1A1SMN1; SMN2MAPK1TP53 | |
| SCHEMBL9878718 | 0.64 | PTGIR (0.47) | ALDH1A1SMN1; SMN2MAPK1TP53RAB9A | |
| SCHEMBL9877360 | 0.63 | SMN1; SMN2 (0.65) | GFERALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9877869 | 0.62 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2POLBTSHR | |
| SCHEMBL9877332 | 0.61 | MAPT (0.54) | ALDH1A1KDM4EHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL8765117 | 0.61 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988725-A | Cardiovascular disorders, antiarrhythmia agents | STERLING DRUG INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0388654-A2 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4916150-A | 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use | STERLING DRUG INC. (US) | 1990-04-10 | — | — | US | disclosed |