Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876523 | 0.91 | PTGER1 (0.39) | CCNA2CDK2PDE4AKCNH2MEN1 | |
| SCHEMBL9877691 | 0.90 | CCNA2 (0.39) | CCNA2CDK2GAAPDE4AKCNH2 | |
| SCHEMBL9876885 | 0.89 | CCNA2 (0.37) | CCNA2CDK2GAANPSR1PDE4A | |
| SCHEMBL9876897 | 0.84 | KDM4E (0.42) | CCNA2CDK2GAANPSR1SRC | |
| SCHEMBL9231716 | 0.84 | CCNA2 (0.38) | CCNA2CDK2GAANPSR1PDE4A | |
| SCHEMBL9876856 | 0.83 | KDM4E (0.43) | CCNA2CDK2GAANPSR1SRC | |
| Fumaric Acid SCHEMBL9234660 | 0.82 | NPSR1 (0.38) | CCNA2CDK2GAANPSR1PDE4A | |
| Maleic Acid SCHEMBL9234653 | 0.82 | NPSR1 (0.38) | CCNA2CDK2GAANPSR1PDE4A | |
| SCHEMBL9876520 | 0.80 | PTGER1 (0.38) | CCNA2CDK2PDE4AKCNH2MEN1 | |
| SCHEMBL9876945 | 0.79 | CCNA2 (0.37) | CCNA2CDK2GAAPDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |