Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | BRAF | P15056 | 15/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877202 | 0.86 | TLR8 (0.67) | KDM4EBRAFTLR8 | |
| SCHEMBL9728825 | 0.86 | TLR8 (0.67) | KDM4EBRAFTLR8 | |
| SCHEMBL9728973 | 0.85 | CLK4 (0.61) | KDM4ETLR8 | |
| SCHEMBL9728968 | 0.85 | CLK4 (0.61) | KDM4ETLR8 | |
| SCHEMBL3172240 | 0.83 | KDM4E (0.80) | KDM4EBRAFTLR8 | |
| SCHEMBL3175469 | 0.83 | KDM4E (0.83) | KDM4EBRAFTLR8 | |
| SCHEMBL9728647 | 0.82 | KDM4E (0.48) | KDM4EBRAFRAF1MAPK14 | |
| SCHEMBL9878320 | 0.82 | KDM4E (0.48) | KDM4EBRAFRAF1MAPK14 | |
| SCHEMBL11464152 | 0.82 | KDM4E (0.81) | KDM4EBRAFTLR8 | |
| SCHEMBL8435070 | 0.81 | KDM4E (1.00) | KDM4EBRAFTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | claimed |