Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.47 |
| ▸ | PIM1 | P11309 | 6/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 10/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728647 | 1.00 | KDM4E (0.48) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9877172 | 0.85 | NTRK1 (0.64) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9728862 | 0.82 | NTRK1 (0.69) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9877207 | 0.82 | KDM4E (0.67) | KDM4EBRAFRAF1MAPK14 | |
| SCHEMBL9728729 | 0.82 | NTRK1 (0.53) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9877259 | 0.81 | NTRK1 (0.43) | NTRK1PIM1CHEK1CDK2CSNK2A1 | |
| SCHEMBL11480970 | 0.81 | BRAF (0.54) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL10842009 | 0.80 | BRAF (0.45) | KDM4EBRAF | |
| SCHEMBL10842005 | 0.80 | BRAF (0.45) | KDM4EBRAF | |
| SCHEMBL3171563 | 0.73 | KDM4E (0.54) | KDM4ENTRK1PIM1CDK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | claimed |