Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | HTT | P42858 | 9/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877301 | 0.88 | TDP1 (0.54) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9878322 | 0.88 | TDP1 (0.54) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9877690 | 0.84 | TDP1 (0.54) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9878157 | 0.82 | ALDH1A1 (0.48) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17046868 | 0.80 | HTT (0.59) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL318630 | 0.80 | HTT (0.59) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29577465 | 0.80 | HTT (0.59) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1133512 | 0.78 | HTT (0.58) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22446563 | 0.76 | L3MBTL1 (0.57) | TDP1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19872051 | 0.76 | HSP90AA1 (0.72) | TDP1MAPTKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161791-B1 | LOW FUEL CONSUMPTION TIRE WITH ALL WEATHER PERFORMANCES | Bridgestone Corporation (JP) | 1988-11-02 | — | — | EP | claimed |
| EP-0161791-A1 | Low fuel consumption tire with all weather performances | Bridgestone Corporation (JP) | 1985-11-21 | — | — | EP | claimed |
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0161791-B1 | LOW FUEL CONSUMPTION TIRE WITH ALL WEATHER PERFORMANCES | Bridgestone Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4624977-A | NATURAL OR SYNTHETIC RUBBER DENATURED NITROSOQUINOLINE, CARBON BLACK | BRIDGESTONE CORPORATION (JP) | 1986-11-25 | — | — | US | disclosed |
| EP-0161791-A1 | Low fuel consumption tire with all weather performances | Bridgestone Corporation (JP) | 1985-11-21 | — | — | EP | disclosed |