Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | CCR1 | P32246 | 3/20 | 0.59 |
| ▸ | CCR8 | P51685 | 3/20 | 0.59 |
| ▸ | COMT | P21964 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | MMP14 | P50281 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046868 | 1.00 | HTT (0.59) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL29577465 | 1.00 | HTT (0.59) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL1133512 | 0.98 | HTT (0.58) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL8344417 | 0.84 | HTT (0.54) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL22446563 | 0.84 | L3MBTL1 (0.57) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL12292143 | 0.84 | HSP90AA1 (0.72) | HTTSLC6A2CCR1CCR8COMT | |
| Tilbroquinol SCHEMBL1441958 | 0.84 | KDM4E (0.72) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL8343238 | 0.84 | HSP90AA1 (0.72) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL12992674 | 0.84 | COMT (0.57) | HTTSLC6A2CCR1CCR8COMT | |
| SCHEMBL19872051 | 0.84 | HSP90AA1 (0.72) | HTTSLC6A2CCR1CCR8COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084897-A | Iron ion detection reagent and preparation method and application thereof | 河南省氟基新材料科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-111875555-B | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2022-07-19 | — | — | CN | claimed |
| CN-111875555-A | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2020-11-03 | — | — | CN | claimed |
| EP-2265677-B1 | CORROSION DETECTION PRODUCT AND METHOD | BATTELLE MEMORIAL INSTITUTE (US) | 2019-05-15 | — | — | EP | claimed |
| CN-103221509-B | Luminophor, the preparation method of luminophor and its application | 波兰科学院物理化学研究所 | 2016-08-03 | — | — | CN | claimed |
| US-9217104-B2 | Luminescent compounds, method of preparation of luminescent compounds and applications thereof | INSTYTUT CHEMII FIZYCZNEJ POLSKIEJAKADEMII NAUK (PL) | 2015-12-22 | — | — | US | claimed |
| CN-103787517-A | Treatment method of circulating water | CHINA PETROLEUM & CHEMICAL | 2014-05-14 | — | — | CN | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| CN-118084897-A | Iron ion detection reagent and preparation method and application thereof | 河南省氟基新材料科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20240148918-A1 | Loading of Alginate Microspheres | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-05-09 | — | — | US | disclosed |
| EP-4301341-A1 | LOADING OF ALGINATE MICROSPHERES | Board of Regents, The University of Texas System (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-117241781-A | Loading of alginate microspheres | 德克萨斯大学系统董事会 | 2023-12-15 | — | — | CN | disclosed |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| EP-1328525-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-A]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002076994-A1 | TUMOR-INHIBITING SILICON COMPOUNDS | FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |
| US-20020002161-A1 | Novel 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole compounds | PHARMACIA & UPJOHN COMPANY | 2002-01-03 | — | — | US | disclosed |
| WO-2001072752-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-a]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |
| US-4002477-A | Diffusion transfer processes and elements using or containing inert transitional metal complex oxidizing agents | EASTMAN KODAK COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3989526-A | IMAGE FORMATION, PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | TERT, TERF2, RNGTT | HTT 178/4885SLC6A2 2961/4885CCR1 4654/4885 |
| US-20020002161-A1 | Novel 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole compounds | HTR1D, HTR1A, HTR1E | HTT 703/4885SLC6A2 273/4885CCR1 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.