Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295727 | 0.81 | ALDH1A1 (0.31) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL9878434 | 0.79 | MEN1 (0.39) | CNR1CNR2TSHRHTTSMN1; SMN2 | |
| SCHEMBL9878147 | 0.76 | — | — | |
| SCHEMBL10792506 | 0.75 | CNR1 (0.44) | CNR1CNR2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10794109 | 0.75 | ALDH1A1 (0.35) | CNR1CNR2TSHRALDH1A1KDM4E | |
| SCHEMBL10792605 | 0.73 | CHRNB2 (0.37) | CNR1CNR2HTTNPSR1ALDH1A1 | |
| SCHEMBL10796814 | 0.73 | PDE2A (0.38) | ALDH1A1 | |
| SCHEMBL4491483 | 0.72 | HRH4 (0.36) | CNR1CNR2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10791610 | 0.72 | CYP2C9 (0.41) | CNR2TSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6694230 | 0.71 | ESR1 (0.47) | TSHRSMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |