Sugi Predict

Sugi Predict / Compounds / SCHEMBL4295727

SCHEMBL4295727

SCHEMBL4295727

CCC(C)N(N=O)c1ccc(N(N=O)C(C)CC)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ HIF1A Q16665 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ TP53 P04637 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ RGS12 O14924 1/20 0.31
▸ USP2 O75604 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ APEX1 P27695 1/20 0.31
▸ BRCA1 P38398 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9878147 0.94 — —
SCHEMBL10794109 0.92 ALDH1A1 (0.35) ALDH1A1TSHRKDM4EMEN1HPGD
SCHEMBL10792605 0.91 CHRNB2 (0.37) ALDH1A1HSD17B10KDM4EMEN1HPGD
SCHEMBL10794153 0.88 SLC2A1 (0.39) ALDH1A1MAPK1USP2PKMHPGD
SCHEMBL10795977 0.88 MCL1 (0.38) ALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL10796814 0.86 PDE2A (0.38) ALDH1A1
SCHEMBL10793061 0.85 ESR1 (0.37) ALDH1A1TSHRMEN1POLBHPGD
SCHEMBL7720749 0.85 ALDH1A1 (0.56) ALDH1A1MAPK1HIF1AHSD17B10TP53
SCHEMBL9877239 0.81 CNR1 (0.36) ALDH1A1HSD17B10TSHRKDM4EMEN1
SCHEMBL7765528 0.79 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117643648-B Injectable self-healing hydrogel dressing and preparation method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 — — CN claimed
CN-122075443-A Targeted nano drug delivery system and preparation method and application thereof — 2026-05-26 — — CN claimed
CN-122005496-A X-ray controllable activated nanoparticle as well as preparation method and application thereof 吉林大学 2026-05-12 — — CN claimed
CN-120053400-A Nanometer autophagy inducing preparation, preparation method and application thereof, and pharmaceutical composition 中国科学院大学 2025-05-30 — — CN claimed
CN-120037909-A Light-operated nitric oxide release hollow monoatomic nano-enzyme, preparation method and application 暨南大学 2025-05-27 — — CN claimed
CN-118987349-B Artificial cornea capable of releasing nitric oxide by light control 山东百多安医疗器械股份有限公司 2025-02-07 — — CN claimed
CN-119185638-A Photothermal/nitric oxide synergistic antibacterial hydrogel wound dressing based on natural plant extract quercetin and preparation method thereof 郑州大学 2024-12-27 — — CN claimed
CN-118987349-A Artificial cornea capable of releasing nitric oxide by light control 山东百多安医疗器械股份有限公司 2024-11-22 — — CN claimed
CN-118453950-B Medical antibacterial dressing and preparation method thereof 吉林省科百医疗器材有限公司 2024-09-13 — — CN claimed
CN-118453950-A Medical antibacterial dressing and preparation method thereof 吉林省科百医疗器材有限公司 2024-08-09 — — CN claimed
CN-115125669-A Ultrasonic-responsive nitric oxide-releasing electrospun membrane and preparation method thereof 华中科技大学同济医学院附属协和医院 2022-09-30 — — CN claimed
CN-114652831-A Near-infrared II-region controlled-release nitric oxide nano carrier material and preparation method and application thereof 暨南大学 2022-06-24 — — CN claimed
US-20220071918-A1 MUSSEL ADHESIVE PROTEIN-BASED PHOTOTHERMAL AGENT AND PHOTOTHERMAL- RESPONSIVE ADHESIVE NANOPARTICLES POSTECH Research and Business Development Foundation (KR) 2022-03-10 — — US claimed
CN-114106354-A Nanocomposite capable of in-situ autocatalytic generation of hydrogen peroxide and sustained release of NO and free radicals, and preparation method and application thereof 暨南大学 2022-03-01 — — CN claimed
CN-110960724-B Medicinal hydrogel and preparation method thereof 暨南大学 2022-02-15 — — CN claimed
EP-3895701-A1 METHOD FOR INCREASING PERMEABILITY OF BLOOD-BRAIN BARRIER POSTECH Research and Business Development Foundation (KR) 2021-10-20 — — EP claimed
US-20210290762-A1 METHOD FOR INCREASING PERMEABILITY OF BLOOD-BRAIN BARRIER POSTECH Research and Business Development Foundation (KR) 2021-09-23 — — US claimed
WO-2020130428-A2 MUSSEL ADHESIVE PROTEIN-BASED PHOTOTHERMAL AGENT, AND PHOTOTHERMAL REACTIVE ADHESIVE NANOPARTICLES 포항공과대학교 산학협력단 2020-06-25 — — WO claimed
US-6395942-B1 N-NITROSO INHIBITOR, ADDING A STABILIZER SUCH AS N,N'-DI-2-BUTYL-1,4-DIAMINOBENZENE OR A PHENOLIC COMPOUND; STYRENE DURING ITS DISTILLATION UOP LLC 2002-05-28 — — US claimed
US-6395943-B1 N-NITROSO INHIBITOR, ADDING A NITROPHENOL COMPOUND SELECTED FROM THE GROUP CONSISTING OF DINITROPHENOL, DINITROCRESOL, 2-SEC-BUTYL-4,6-DINITROPHENOL; STYRENE DURING ITS DISTILLATION UOP LLC 2002-05-28 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210290762-A1 METHOD FOR INCREASING PERMEABILITY OF BLOOD-BRAIN BARRIER MMP9, MMP10, MMP11 ALDH1A1 1428/4885MAPK1 1984/4885HIF1A 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.